Generation of Pluripotent Stem Cells from Neonatal Mouse Testis
نویسندگان
چکیده
منابع مشابه
Generation of Pluripotent Stem Cells from Neonatal Mouse Testis
Although germline cells can form multipotential embryonic stem (ES)/embryonic germ (EG) cells, these cells can be derived only from embryonic tissues, and such multipotent cells have not been available from neonatal gonads. Here we report the successful establishment of ES-like cells from neonatal mouse testis. These ES-like cells were phenotypically similar to ES/EG cells except in their genom...
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Severe spinal cord injury and diseases involving motoneuron loss cause miserable outcomes in clinical settings, and no therapy can reverse the patients[ disabilities in the final stages of the disease. Cell replacement therapy, however, is a possible approach for treating irreversible damage and loss of spinal motoneurons. Embryonic stem cells have been considered for use as graft cells and ana...
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ژورنال
عنوان ژورنال: Cell
سال: 2004
ISSN: 0092-8674
DOI: 10.1016/j.cell.2004.11.011